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Celexo® Enzyme Powder Wash

Mild Enzymatic Exfoliation and Deep Cleansing Perfected by Exosome Technology

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In professional skin treatment programs, effective preparation determines how well subsequent activities are absorbed and performed. Celexo® Enzyme Powder Wash, developed by ABio Materials Co. in pharmaceutical-grade facilities in Korea, delivers mild enzymatic exfoliation and deep cleansing through a concentrated Papain formulation enriched with Exo-Cica. Designed as Pre Care Step 1 in the Celexo® Exo-Therapy Skincare Protocol, this powder cleanser gently dissolves outer-layer buildup, loosens accumulated dead skin cells, and readies the complexion to receive booster actives for maximum uptake. This page covers the scientific principles, clinical applications, and evidence-based benefits of Celexo® Enzyme Powder Wash.

The Science of
Celexo® Enzyme Powder Wash

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1

Papain Enzymatic Action

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This professional cleanser features 2,000 ppm of papain, a plant-derived enzyme that targets and dissolves the protein bonds of dead keratinocytes. Because this enzymatic process exfoliates without physical abrasion, it is ideal for pre-procedure priming where tissue integrity must be maintained. Removing this barrier clears the pathways for enhanced penetration of subsequent actives.

2

Exo-Cica Complex Integration

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The formulation combines exfoliation with Exo-Cica, a plant-derived exosome complex from the Celexo® Exo-Therapy line. By delivering anti-inflammatory signals during the cleansing step, it immediately calms potential irritation. This dual-action process minimizes sensitization and ensures skin comfort ahead of the main booster treatment.

3

Powder-to-Foam Activation

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The dry powder keeps the enzymes stable and potent during storage. Once mixed with water, it activates into a gentle foam that distributes evenly. This fresh activation ensures maximum enzyme efficacy at the moment of use, allowing the lather to thoroughly cleanse and exfoliate simultaneously.

4

Protocol Positioning and Cumulative Benefit

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As Step 1 of the Celexo® Exo-Therapy Skincare Protocol, the Enzyme Powder Wash removes sebum, debris, and dead skin cells, perfectly prepping your complexion. By clearing this barrier, it maximizes the absorption and efficacy of the subsequent toner, booster, and post-care treatments.

Key Benefits of Celexo® Enzyme Powder Wash

Mild Enzymatic Exfoliation

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Papain at 2,000 ppm dissolves dead-cell buildup through targeted proteolytic activity, refining the complexion without abrasive physical friction.

Simultaneous Soothing Action

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Exo-Cica delivers calming bioactive signals during cleansing to reduce reactive responses and maintain comfort throughout the exfoliation process.

Enhanced Absorption Preparation

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By clearing surface accumulation and loosening congestion, the formulation may help open pathways for improved uptake of subsequent booster actives.

Stable Powder Activation

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This format preserves enzymatic potency until activation, ensuring freshly delivered active performance with each use.

Gentle Pre-Treatment Compatibility

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Formulated for use ahead of aesthetic procedures, including microneedling, MTS, and laser applications, where surface clarity and tissue integrity are both required.

Protocol-Integrated Design

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Developed specifically as the first step in the Celexo® Exo-Therapy Skincare Protocol, supporting seamless transition into Pre Care Step 2 and the Main Booster phase.

Clinical Applications

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This enzymatic cleanser is intended for professional clinical settings where a reliable, non-abrasive preparatory cleanser is required ahead of device-assisted or booster-based procedures.

Common Use Cases:

Pre-procedure preparation for microneedling, MTS, and laser treatments requires a clear, residue-free complexion before booster application.

Routine enzymatic purification for complexion types prone to outer layer congestion, uneven texture, or sebum accumulation that may impede active ingredient uptake.

Sensitive pre-treatment preparation for individuals who may not tolerate physical exfoliants but require effective epidermal renewal before professional therapy.

Integration is the foundational step in the complete Celexo® Exo-Therapy Skincare Protocol for clinical and aesthetic practice settings.

Preparatory purification ahead of Celexo® Refine Bubble Toner application to establish a fully open and receptive epidermal layer for the secondary exfoliation step.

Application Protocol

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Skin Preparation:

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Dispense a small amount of powder into clean, dry palms. The quantity can be adjusted based on the desired cleansing intensity and the individual’s complexion response.

Activation:

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Add a few drops of water to the powder in the palm and work together until a gentle foam forms. The enzymatic actives are released upon contact with moisture.

Application Method:

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Apply the activated foam to the face using gentle circular motions. Avoid vigorous rubbing. Allow the foam to remain on the skin for 30 to 60 seconds to permit enzymatic activity.

Rinsing:

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Rinse thoroughly with lukewarm water, ensuring no residue remains. Pat the complexion dry with a clean cloth.

Frequency:

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For use as part of the clinical therapy protocol, apply before each session ahead of the Celexo® Refine Bubble Toner. Frequency is determined by the treating practitioner based on individual assessment.

Post-Cleansing Transition:

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Proceed immediately to Celexo® Refine Bubble Toner as Step 2 of the Pre Care phase to continue preparing absorption pathways before the Main Booster application.

Papain Enzyme Technology and Safety

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Papain is a well-established plant-derived enzyme used across clinical and advanced skincare formulations for its reliable, selective exfoliating properties. Unlike alpha-hydroxy or beta-hydroxy acids, which chemically dissolve intercellular bonds, Papain acts via enzyme-driven hydrolysis of epidermal proteins, offering a distinct and complementary exfoliation pathway. At a 2,000 ppm concentration in this formulation, Papain provides effective keratolytic activity within a range calibrated for pre-treatment preparation rather than aggressive resurfacing.

The inclusion of Exo-Cica alongside Papain further supports tolerance of the complexion, providing concurrent calming activity that may offset any transient sensitivity associated with enzymatic cleansing. This formulation approach reflects ABio Materials Co.’s focus on delivering professional-grade efficacy within a tolerance-conscious framework suitable for use ahead of advanced aesthetic procedures.

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Formulation Science and Quality Standards

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This product is manufactured at ABio Materials Co. facilities in Korea, certified to ISO 13485 and GMP standards. The powder format is engineered for formulation stability, ensuring that Papain retains its proteolytic activity from production through the point of use. Each batch undergoes rigorous quality evaluation, including Papain concentration and activity verification, Exo-Cica component integrity confirmation, particle consistency and dispersion testing, microbiological safety assessment per USP protocols, performance under standardized water-contact conditions, and packaging integrity to maintain ingredient stability throughout the product lifecycle.

This manufacturing standard ensures consistent pre-treatment performance and distinguishes this cleanser from conventional alternatives lacking pharmaceutical-grade enzyme concentration or validated exosome integration.

Frequently Asked Questions

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The product is formulated with Papain at 2,000 ppm for enzymatic exfoliation and Exo-Cica, a proprietary plant-derived exosome complex, for concurrent calming activity. Full technical data is available upon request.

It is designed for pre-treatment preparation in professional settings, including use before microneedling, MTS, laser, and other device-assisted procedures. Its gentle keratolytic action may help clarify the area without compromising tissue integrity prior to treatment.

Papain-based enzymatic exfoliation selectively degrades keratin proteins rather than relying on physical abrasion or acid-based dissolution. This mechanism may offer a gentler alternative for complexion types that require epidermal renewal before professional therapy.

Application frequency is determined by the treating practitioner based on individual assessment and the specific procedure being performed. As Step 1 of the Celexo® Exo-Therapy Skincare Protocol, it is intended for use before each treatment session.

This cleanser is manufactured by ABio Materials Co. in Korea, in facilities certified to ISO 13485 and GMP standards.

It is available through authorized professionals and distribution channels. Visit a-biousa.com to explore the complete Celexo® Exo-Therapy product line and connect with the ABio Materials USA team.

Establishing the Foundation for Professional-Grade Exosome Therapy

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Celexo® Enzyme Powder Wash represents the precision-engineered starting point of the Celexo® Exo-Therapy Skincare Protocol, where enzyme science and exosome technology converge to prepare the complexion for professional-grade treatment. By establishing a clean, clarified, and receptive base from the first step, ABio Materials Co. ensures that every subsequent phase of the protocol can perform at its intended level.

To learn more about Celexo® Enzyme Powder Wash or explore the complete Celexo® Exo-Therapy line, visit a-biousa.com.

Contact Us

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Connect With ABio Materials USA Inc

We welcome inquiries from partners, distributors, and industry professionals worldwide. Whether you are interested in our product portfolio, ODM/OEM collaboration, or research support, our team is committed to providing clear, timely, and knowledgeable assistance. Reach out to learn how our bio-material technologies and exosome expertise can support your clinical, aesthetic, or research goals.

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